PHARMACOLOGICAL INNOVATIONS IN VETERINARY MEDICINE: EVALUATING THE EFFICACY AND SAFETY OF NOVEL DRUG THERAPIES FOR PAIN MANAGEMENT IN LARGE ANIMAL SURGERY

Authors

  • Hamza Naveed DVM, MPhil (Veterinary Pharmacology) Department of Veterinary Pharmacology Faculty of Veterinary Sciences National Institute of Animal Health Sciences, Faisalabad, Pakistan. Author
  • Saira Mehmood VM, MPhil (Veterinary Pharmacology) Department of Veterinary Pharmacology Faculty of Veterinary Sciences National Institute of Animal Health Sciences, Faisalabad, Pakistan. Author

Keywords:

Postoperative Pain, Multimodal Analgesia, Large Animal Surgery, Nsaids, Opioids, Extended-Release Formulations, Veterinary Pain Management

Abstract

This research paper evaluates the efficiency and safety of new pharmacological interventions in postoperative pain management in large animal surgery specifically equines and bovines.  The paper reviews some of the multimodal analgesic programs that combine traditional drugs, such as NSAIDs and opioids, with new interventions, such as long-acting formulations and specific analgesics.  The efficacy of these regimens in the alleviation of pain, reduction of side effects, and recovery was assessed using the randomized controlled trial (RCT) methodology.  The study involved the use of subjective pain scale and objective physiological indices to measure the effectiveness of analgesic.  Findings indicate that multimodal analgesia is much more effective in pain management and better recovery results, with a reduced number of side effects and satisfied patients.  These findings demonstrate that multimodal analgesia would be beneficial in managing pain during large animal surgery, which would prove to be healthier to the animals and would aid them to recover sooner.  To have these regimens in clinical practice, their pharmacodynamics and cost-effectiveness require further investigation.

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Published

2025-12-31